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EXPANDED SECOND EDITION. Inborn Errors of Metabolism by Garrod, Archibald E.

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$300.00

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Seller: Biomed Rare Books LLC, ABAA, ILAB

Title: EXPANDED SECOND EDITION. Inborn Errors of Metabolism
Author: Garrod, Archibald E.
Seller: Biomed Rare Books LLC, ABAA, ILAB (United States)
Description: London: Henry Frowde and Hodder & Stoughton, 1923. Second edition. 1923 LANDMARK MONOGRAPH BY BRITISH PHYSICIAN SIR ARCHIBALD GARROD--THE FIRST TO ATTRIBUTE DISEASES RESULTING TO INBORN ERRORS OF METABOLISM--CONTAINING DESCRIPTIONS OF "GARROD'S TETRAD." 7 1/2 inches tall hardcover, red cloth binding, title stamped on cover and gilt title to spine, [i-viii], 216 pp, spine faded, binding tight, light foxing to endpapers, pages clean and unmarked, very good in custom archival mylar cover. GARRISON - MORTON No. 3921 for the first edition of 1909. SIR ARCHIBALD EDWARD GARROD (1857-1936) was the son of the physician, Alfred Baring Garrod, who diagnosed and studied rheumatoid arthritis. Although his father initially intended for Archibald to study business, his teachers recognized and encouraged him to go into the field of science and medicine. Garrod studied medicine at Oxford University and became a physician. Garrod was studying the human disorder alkaptonuria. He collected family history information (as well as urine) from his patients. Based on discussions with Mendel advocate William Bateson, Garrod deduced that alkaptonuria is a recessive disorder. In 1902, Garrod published The Incidence of Alkaptonuria: a Study in Chemical Individuality. This is the first published account of a case of recessive inheritance in humans. Garrod was also the first to propose the idea that diseases were "inborn errors of metabolism." He believed that diseases were the result of missing or false steps in the body's chemical pathways. Over the next decade he developed an understanding of the possible nature of inherited diseases of metabolism. He described the nature of recessive inheritance of most enzyme defects. In 1908, the core of this work was presented as the Croonian Lectures to the Royal College of Physicians, entitled Inborn Errors of Metabolism and published the following year. Garrod expanded his metabolic studies to cover cystinuria, pentosuria, and albinism. These three inborn errors, along with alkaptonuria are collectively called Garrod's tetrad. In 1923 he summarized these studies in an expanded edition of his best known work (offered here). Garrod attributed a biochemical role to genes, and laid the groundwork for the next wave of discovery — the molecular basis of inheritance.

An Enigma...Written for the Gentleman's Journal of 1692 by Wulling, Emerson G.

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Seller: Rulon-Miller Books

Title: An Enigma...Written for the Gentleman's Journal of 1692
Author: Wulling, Emerson G.
Seller: Rulon-Miller Books (United States)
Description: Minneapolis, 1929. Square leaflet, pp. [4]; covers lined and lettered in maroon, fine. "Perhaps devotees of the Pipe will find a whisp of pleasure in this modest piece." Rulon-Miller, Wulling 4.

Nanette's Baguette by Willems, Mo

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$20.00

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Seller: Kenneth Mallory Bookseller. ABAA

Title: Nanette's Baguette
Author: Willems, Mo
Seller: Kenneth Mallory Bookseller. ABAA (United States)
ISBN: 9781484722862
Condition: Very good
Description: NY: Hyperion, 2016. Hardcover. Very good. Hardcover. First Edition. Very good hardback in a very good dustjacket.

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